Management and Prevention Strategies for Non-communicable Diseases (NCDs) and Their Risk Factors

Non-communicable diseases (NCDs) are of increasing concern for society and national governments, as well as globally due to their high mortality rate. The main risk factors of NCDs can be classified into the categories of self-management, genetic factors, environmental factors, factors of medical conditions, and socio-demographic factors. The main focus is on the elements of self-management and to reach a consensus about the influence of food on risk management and actions toward the prevention of NCDs at all stages of life. Nutrition interventions are essential in managing the risk of NCDs. As they are of the utmost importance, this review highlights NCDs and their risk factors and outlines several common prevention strategies. We foresee that the best prevention management strategy will include individual (lifestyle management), societal (awareness management), national (health policy decisions), and global (health strategy) elements, with target actions, such as multi-sectoral partnership, knowledge and information management, and innovations. The most effective preventative strategy is the one that leads to changes in lifestyle with respect to diet, physical activities, cessation of smoking, and the control of metabolic disorders

The rise of ransomware: a review of attacks, detection techniques, and future challenges

Cybersecurity is important in the field of information technology. One most recent pressing issue is information security. When we think of cybersecurity, the first thing that comes to mind is cyber-attacks, which are on the rise, such as Ransomware. Various governments and businesses take a variety of measures to combat cybercrime. People are still concerned about ransomware, despite numerous cybersecurity precautions. In ransomware, the attacker encrypts the victim's files/data and demands payment to unlock the data. Cybersecurity is a collection of tools, regulations, security guards, security ideas, guidelines, risk management, activities, training, insurance, best practices, and technology used to secure the cyber environment, organization, and user assets. This paper analyses ransomware attacks, techniques for dealing with these attacks, and future challenges

Lightweight encryption technique to enhance medical image security on internet of medical things applications

The importance of image security in the field of medical imaging is challenging. Several research works have been conducted to secure medical healthcare images. Encryption, not risking loss of data, is the right solution for image confidentiality. Due to data size limitations, redundancy, and capacity, traditional encryption techniques cannot be applied directly to e-health data, especially when patient data are transferred over the open channels. Therefore, patients may lose the privacy of data contents since images are different from the text because of their two particular factors of loss of data and confidentiality. Researchers have identified such security threats and have proposed several image encryption techniques to mitigate the security problem. However, the study has found that the existing proposed techniques still face application-specific several security problems. Therefore, this paper presents an efficient, lightweight encryption algorithm to develop a secure image encryption technique for the healthcare industry. The proposed lightweight encryption technique employs two permutation techniques to secure medical images. The proposed technique is analyzed, evaluated, and then compared to conventionally encrypted ones in security and execution time. Numerous test images have been used to determine the performance of the proposed algorithm. Several experiments show that the proposed algorithm for image cryptosystems provides better efficiency than conventional techniques

Noninvasive ventilation in COVID-19 patients aged ≥ 70 years—a prospective multicentre cohort study

Funding Information: COVIP study did not have any funding. Publication of this article was funded by the Priority Research Area qLife under the program “Excellence Initiative – Research University” at the Jagiellonian University in Krakow (06/IDUB/2019/94). Publisher Copyright: © 2022, The Author(s).Background: Noninvasive ventilation (NIV) is a promising alternative to invasive mechanical ventilation (IMV) with a particular importance amidst the shortage of intensive care unit (ICU) beds during the COVID-19 pandemic. We aimed to evaluate the use of NIV in Europe and factors associated with outcomes of patients treated with NIV. Methods: This is a substudy of COVIP study—an international prospective observational study enrolling patients aged ≥ 70 years with confirmed COVID-19 treated in ICU. We enrolled patients in 156 ICUs across 15 European countries between March 2020 and April 2021.The primary endpoint was 30-day mortality. Results: Cohort included 3074 patients, most of whom were male (2197/3074, 71.4%) at the mean age of 75.7 years (SD 4.6). NIV frequency was 25.7% and varied from 1.1 to 62.0% between participating countries. Primary NIV failure, defined as need for endotracheal intubation or death within 30 days since ICU admission, occurred in 470/629 (74.7%) of patients. Factors associated with increased NIV failure risk were higher Sequential Organ Failure Assessment (SOFA) score (OR 3.73, 95% CI 2.36–5.90) and Clinical Frailty Scale (CFS) on admission (OR 1.46, 95% CI 1.06–2.00). Patients initially treated with NIV (n = 630) lived for 1.36 fewer days (95% CI − 2.27 to − 0.46 days) compared to primary IMV group (n = 1876). Conclusions: Frequency of NIV use varies across European countries. Higher severity of illness and more severe frailty were associated with a risk of NIV failure among critically ill older adults with COVID-19. Primary IMV was associated with better outcomes than primary NIV. Clinical Trial RegistrationNCT04321265, registered 19 March 2020, https://clinicaltrials.gov.publishersversionpublishe

Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial

Background Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients. We aimed to assess the effects of early administration of tranexamic acid on death, hysterectomy, and other relevant outcomes in women with post-partum haemorrhage. Methods In this randomised, double-blind, placebo-controlled trial, we recruited women aged 16 years and older with a clinical diagnosis of post-partum haemorrhage after a vaginal birth or caesarean section from 193 hospitals in 21 countries. We randomly assigned women to receive either 1 g intravenous tranexamic acid or matching placebo in addition to usual care. If bleeding continued after 30 min, or stopped and restarted within 24 h of the first dose, a second dose of 1 g of tranexamic acid or placebo could be given. Patients were assigned by selection of a numbered treatment pack from a box containing eight numbered packs that were identical apart from the pack number. Participants, care givers, and those assessing outcomes were masked to allocation. We originally planned to enrol 15 000 women with a composite primary endpoint of death from all-causes or hysterectomy within 42 days of giving birth. However, during the trial it became apparent that the decision to conduct a hysterectomy was often made at the same time as randomisation. Although tranexamic acid could influence the risk of death in these cases, it could not affect the risk of hysterectomy. We therefore increased the sample size from 15 000 to 20 000 women in order to estimate the effect of tranexamic acid on the risk of death from post-partum haemorrhage. All analyses were done on an intention-to-treat basis. This trial is registered with ISRCTN76912190 (Dec 8, 2008); ClinicalTrials.gov, number NCT00872469; and PACTR201007000192283. Findings Between March, 2010, and April, 2016, 20 060 women were enrolled and randomly assigned to receive tranexamic acid (n=10 051) or placebo (n=10 009), of whom 10 036 and 9985, respectively, were included in the analysis. Death due to bleeding was significantly reduced in women given tranexamic acid (155 [1·5%] of 10 036 patients vs 191 [1·9%] of 9985 in the placebo group, risk ratio [RR] 0·81, 95% CI 0·65–1·00; p=0·045), especially in women given treatment within 3 h of giving birth (89 [1·2%] in the tranexamic acid group vs 127 [1·7%] in the placebo group, RR 0·69, 95% CI 0·52–0·91; p=0·008). All other causes of death did not differ significantly by group. Hysterectomy was not reduced with tranexamic acid (358 [3·6%] patients in the tranexamic acid group vs 351 [3·5%] in the placebo group, RR 1·02, 95% CI 0·88–1·07; p=0·84). The composite primary endpoint of death from all causes or hysterectomy was not reduced with tranexamic acid (534 [5·3%] deaths or hysterectomies in the tranexamic acid group vs 546 [5·5%] in the placebo group, RR 0·97, 95% CI 0·87-1·09; p=0·65). Adverse events (including thromboembolic events) did not differ significantly in the tranexamic acid versus placebo group. Interpretation Tranexamic acid reduces death due to bleeding in women with post-partum haemorrhage with no adverse effects. When used as a treatment for postpartum haemorrhage, tranexamic acid should be given as soon as possible after bleeding onset. Funding London School of Hygiene & Tropical Medicine, Pfizer, UK Department of Health, Wellcome Trust, and Bill & Melinda Gates Foundation

Global injury morbidity and mortality from 1990 to 2017 : results from the Global Burden of Disease Study 2017

Correction:Background Past research in population health trends has shown that injuries form a substantial burden of population health loss. Regular updates to injury burden assessments are critical. We report Global Burden of Disease (GBD) 2017 Study estimates on morbidity and mortality for all injuries. Methods We reviewed results for injuries from the GBD 2017 study. GBD 2017 measured injury-specific mortality and years of life lost (YLLs) using the Cause of Death Ensemble model. To measure non-fatal injuries, GBD 2017 modelled injury-specific incidence and converted this to prevalence and years lived with disability (YLDs). YLLs and YLDs were summed to calculate disability-adjusted life years (DALYs). Findings In 1990, there were 4 260 493 (4 085 700 to 4 396 138) injury deaths, which increased to 4 484 722 (4 332 010 to 4 585 554) deaths in 2017, while age-standardised mortality decreased from 1079 (1073 to 1086) to 738 (730 to 745) per 100 000. In 1990, there were 354 064 302 (95% uncertainty interval: 338 174 876 to 371 610 802) new cases of injury globally, which increased to 520 710 288 (493 430 247 to 547 988 635) new cases in 2017. During this time, age-standardised incidence decreased non-significantly from 6824 (6534 to 7147) to 6763 (6412 to 7118) per 100 000. Between 1990 and 2017, age-standardised DALYs decreased from 4947 (4655 to 5233) per 100 000 to 3267 (3058 to 3505). Interpretation Injuries are an important cause of health loss globally, though mortality has declined between 1990 and 2017. Future research in injury burden should focus on prevention in high-burden populations, improving data collection and ensuring access to medical care.Peer reviewe

Watermarking text document image using pascal triangle approach

Emergence of internet and other modern digital applications such as electronic publishing and digital library make it easy to reproduce and re-distribute digital contents thus give room to so many copyright violations including plagiarism and other illegal use of contents that need to be resolved. One way to prevent these illicit activities is to watermark the document before distribution. Thus, this research proposes a new text document image watermarking algorithm which emphasises on two most important measures, visual quality and robustness. In order to boost these measures, third least significant bit has been used for insertion. In addition, to further strengthen the technique, the Pascal Triangle is applied to determine the best position for embedding. Experimental results on the standard dataset have revealed that the proposed watermarking has achieved very encouraging results with PSNR and NCC averaged 54.95db and 0.98 respectively. In terms of robustness against adding noise attacks, the performance of the proposed technique, however, is less satisfactory

Challenges in multi-layer data security for video steganography

The steganography is prone to number of attacks such as geomatical, salt & pepper, gaussian, median filtering, attacks. To overcome these problems, the cryptography and error correction codes are comes in the pictures and hybrid with steganography algorithms. The cryptography algorithms add one layer of security on steganography algorithms and error correction codes improves the robustness of steganography algorithms. On the other side, the hybridization of the algorithms, increase memory complexity and increase computation time for data embedding. Thus, in this paper a review on multi-layer algorithms for video steganography is done. This paper comprehensively reviews the steganography, spatial and frequency domain techniques hybrid with cryptography and error correction techniques. In-depth analysis on published literatures revealed that the spatial domain techniques require shorter computation time for data embedding and provide higher data hiding capacity than frequency domain methods. Performance of such techniques was evaluated in terms of visual quality and robustness parameters. Present challenges and future trends towards the improvement of the multi-layer data security in video steganography are discussed to provide the taxonomy for further navigation

CHALLENGES IN MULTI-LAYER DATA SECURITY FOR VIDEO STEGANOGRAPHY

The steganography is prone to number of attacks such as geomatical, salt & pepper, gaussian, median filtering, attacks. To overcome these problems, the cryptography and error correction codes are comes in the pictures and hybrid with steganography algorithms. The cryptography algorithms add one layer of security on steganography algorithms and error correction codes improves the robustness of steganography algorithms. On the other side, the hybridization of the algorithms, increase memory complexity and increase computation time for data embedding. Thus, in this paper a review on multi-layer algorithms for video steganography is done. This paper comprehensively reviews the steganography, spatial and frequency domain techniques hybrid with cryptography and error correction techniques. In-depth analysis on published literatures revealed that the spatial domain techniques require shorter computation time for data embedding and provide higher data hiding capacity than frequency domain methods. Performance of such techniques was evaluated in terms of visual quality and robustness parameters. Present challenges and future trends towards the improvement of the multi-layer data security in video steganography are discussed to provide the taxonomy for further navigation